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Praziquantel, sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections.It should not be used for cysticercosis that involves the eye. It is taken by mouth.

Side effects may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. While it may be used during pregnancy, it is not recommended for use during breastfeeding. Praziquantel is in the anthelmintic class of medications. It works partly by affecting the function of the worm’s sucker.

Praziquantel was approved for medical use in the United States in 1982. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 0.4 to 18.15 USD per day. In the United States a typical course of treatment costs 100 to 200 USD.


IUPAC: (RS)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one